Neurotrophin; Abrineurin
腦源性神經營養因子(BDNF),或稱abrineurin,是一種蛋白質,由BDNF基因編碼。它是神經營養素家族的成員,與典型的神經生長因子有關。神經營養因子存在于大腦和周邊地區。BDNF作用于中樞神經系統和外周神經系統的某些神經元,幫助支持現有神經元的生存,并鼓勵新神經元和突觸的生長和分化。在大腦中,它在海馬體、皮層和基底前腦--對學習、記憶和高級思維至關重要的區域中活躍。BDNF還在視網膜、腎臟、前列腺、運動神經元和骨骼肌中表達,在唾液中也有發現。BDNF本身對長期記憶很重要。
可檢測樣本中人的BDNF,且與其類似物無明顯交叉反應。
由于實驗操作條件的不同( 如操作者、移液技術、洗板技術和穩定條件等),標準曲線的OD值會有所差異。以下數據和曲線僅供參考,實驗者需根據自己的實驗建立標準曲線。
注意:本圖僅供參考,應以同次試驗標準品所繪標準曲線計算標本含量。
板內變異系數小于10%,板間變異系數小于10%
在選取的健康人血清、血漿、細胞培養上清中加入3個不同濃度水平的人BDNF,計算回收率
分別在選取的4份健康人血清、血漿、細胞培養上清中加入高濃度人BDNF,在標準曲線動力學范圍內進行稀釋,評估線性。
注:ELISA試劑盒檢測范圍等數據,因檢測樣本 的不同而調整,實際數據以隨貨說明書為準。
Comparison of retinal degeneration treatment with four types of different mesenchymal stem cells, human induced pluripotent stem cells and RPE cells in a rat retinal degeneration model
Rank: IF 6.1
Journal: Journal of Translational Medicine
Year: 2023
DOI: 10.1186/s12967-023-04785-1
Effects of esketamine on postoperative negative emotions and early cognitive disorders in patients undergoing non-cardiac thoracic surgery: A randomized controlled trial
Rank: IF 5
Journal: Journal of Clinical Anesthesia
Year: 2024
DOI: 10.1016/j.jclinane.2024.111447
Serum cytokines-based biomarkers in the diagnosis and monitoring of therapeutic response in patients with major depressive disorder
Rank: IF 4.8
Journal: International Immunopharmacology
DOI: 10.1016/j.intimp.2023.110108
Effects of Sport Stacking on Neuropsychological, Neurobiological, and Brain Function Performances in Patients With Mild Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Controlled Trial.
Rank: IF 4.1
Journal: Frontiers in Aging Neuroscience
Year: 2022
DOI: 10.3389/fnagi.2022.910261
Evidence of a Relationship Between Plasma Leptin, Not Nesfatin-1, and Craving in Male Alcohol-Dependent Patients After Abstinence
Rank: IF 3.9
Journal: Frontiers in Endocrinology
Year: 2020
DOI: 10.3389/fendo.2020.00159
Association of plasma BDNF and MMP-9 levels with mild cognitive impairment: a matched case-control study
Rank: IF 3.8
Journal: Scientific Reports
DOI: 10.1038/s41598-024-81895-w
Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Protracted Alcohol Withdrawal Symptoms in Male Alcohol-Dependent Patients
Rank: IF 3.2
Journal: Frontiers in Psychiatry
Year: 2021
DOI: 10.3389/fpsyt.2021.678594
Effect of sacubitril/valsartan on brain natriuretic peptide level and prognosis of acute cerebral infarction
Rank: IF 2.9
Journal: PLoS ONE
DOI: 10.1371/journal.pone.0291754
Effects of Sport Stacking on Cognition in Patients With Mild Alzheimer’s Disease and MCI: Preliminary Findings of Randomized Controlled Trial
Journal: Journal of Geriatric Psychiatry and Neurology
DOI: 10.1177/08919887231195227
Application effect of sevoflurane combined with remifentanil intravenous inhalation anesthesia in patients undergoing laparoscopic radical resection of cervical cancer
Rank: IF 1.7
Journal: American Journal of Translational Research
DOI: