17B-Estradiol; Oestradiol; Beta-Estradiol
雌二醇(Estradiol,E2),亦稱“動情素”、“求偶素”。化學式 C18H24O2, 分子量為 272.38,有α,β兩種類型,雌激素的一種。含量最多,活性也最 強。由卵巢內卵泡的顆粒細胞分泌,其代謝物是雌酮及雌三醇。含 18 個碳 原子。其靶器官為子宮、陰道、輸卵管和垂體。可作為一種為經皮膚吸收的 雌激素治療劑。雌激素能促使細胞合成 DNA、RNA 和相應組織內各種不同 的蛋白質。
可檢測樣本中大鼠的E2,且與其類似物無明顯交叉反應。
由于實驗操作條件的不同( 如操作者、移液技術、洗板技術和穩定條件等),標準曲線的OD值會有所差異。以下數據和曲線僅供參考,實驗者需根據自己的實驗建立標準曲線。
注意:本圖僅供參考,應以同次試驗標準品所繪標準曲線計算標本含量。
板內變異系數小于10%,板間變異系數小于10%
在選取的健康大鼠血清、血漿、細胞培養上清中加入3個不同濃度水平的大鼠E2,計算回收率
分別在選取的4份健康大鼠血清、血漿、細胞培養上清中加入高濃度大鼠E2,在標準曲線動力學范圍內進行稀釋,評估線性。
注:ELISA試劑盒檢測范圍等數據,因檢測樣本 的不同而調整,實際數據以隨貨說明書為準。
Effects of Bisphenol A on reproductive toxicity and gut microbiota dysbiosis in male rats
Rank: IF 6.2
Journal: Ecotoxicology and Environmental Safety
Year: 2022
DOI: 10.1016/j.ecoenv.2022.113623
Exploring the mechanism of Semen Cuscutae processed with salt solution in improving kidney deficiency miscarriage based on serum pharmacochemistry and network pharmacology
Rank: IF 5.3
Journal: Arabian Journal of Chemistry
Year: 2023
DOI: 10.1016/j.arabjc.2023.105456
Bu-shen-zhu-yun decoction inhibits granulosa cell apoptosis in rat polycystic ovary syndrome through estrogen receptor α-mediated PI3K/AKT/mTOR pathway
Rank: IF 4.8
Journal: Journal of Ethnopharmacology
Year: 2021
DOI: 10.1016/j.jep.2021.114862
Characterization of the volatile profile and its estrogenic activity in Kadsura coccinea fruit.
DOI: 10.1016/j.jep.2023.116341
A Chinese herbs complex ameliorates gut microbiota dysbiosis induced by intermittent cold exposure in female rats
Rank: IF 4
Journal: Frontiers in Microbiology
DOI: 10.3389/fmicb.2022.1065780
Dietary α-Linolenic Acid-Rich Flaxseed Oil Exerts Beneficial Effects on Polycystic Ovary Syndrome Through Sex Steroid Hormones—Microbiota—Inflammation Axis in Rats
Rank: IF 3.9
Journal: Frontiers in Endocrinology
Year: 2020
DOI: 10.3389/fendo.2020.00284
An integrated study of hormone-related sarcopenia for modeling and comparative transcriptome in rats
DOI: 10.3389/fendo.2023.1073587
To explore the mechanism of acupoint application in the treatment of primary dysmenorrhea by 16S rDNA sequencing and metabolomics
Year: 2024
DOI: 10.3389/fendo.2024.1397402
Peptide TQS169 prevents osteoporosis in rats by enhancing osteogenic differentiation and calcium absorption
Rank: IF 3.8
Journal: Journal of Functional Foods
Year: 2018
DOI: 10.1016/j.jff.2018.08.021
Placental mesenchymal stem cells ameliorate NLRP3 inflammasome-induced ovarian insufficiency by modulating macrophage M2 polarization
Journal: Journal of Ovarian Research
DOI: 10.1186/s13048-023-01136-y